Cord Blood Lipid Profile : Maternal Lipid Levels Across Pregnancy Impact The Umbilical Cord Blood Lipidome And Infant Birth Weight Scientific Reports / Detection of lipid profile in umbilical cord blood of term newborns could identify neonates with a higher risk of coronary artery disease.. The distribution of newborns according to their total cholesterol levels is depicted in figure 1. The cord blood lipid parameters screening of neonates in this part of southern rajasthan were almost comparable with other reports. Mean cholesterol levels, triglyceride levels, ldl cholesterol levels and vldl levels were significantly higher in the sga group than that in the aga group (p < 0.01). During pregnancy, as well as in fetal development, there is high demand of choline 15 , thus it is conceivable that insufficient maternal choline availability may have mediated the downregulation in phospholipid levels in the. Multiple linear regression models were developed to estimate the association of exposure to air pollution and traffic indicators with cord blood lipid profile controlled for relevant covariates.
The aim of the present study was for the first time in iran to assess the cord blood lipid profile of neonates, as well as some of its environmental influencing factors. Detection of lipid profile in umbilical cord blood of term newborns could identify neonates with a higher risk of coronary artery disease. The relationship between cord blood lipid profile with bmi and gestational age of the study population is presented in. Cases having family history of cad and ht have hypertriglyceridemia, hypercholesterolemia and hyperlipidemia and have risk of developing atherosclerosis in their later life. Atherosclerosis begins early in life, and the studies conducted on cord blood lipid profile had inconsistent
Table 2presents the relationship of cord blood lipid profile with birth weight and gestational age. There is evidence that cord blood lipid levels may partly reflect the maternal lipid profile during late pregnancy. Lipid profile was compared between preterm and term neonates, sga and aga neonates. During pregnancy, as well as in fetal development, there is high demand of choline 15 , thus it is conceivable that insufficient maternal choline availability may have mediated the downregulation in phospholipid levels in the. Coronary heart disease is one of the major causes of morbidity and mortality in current era. Atherosclerosis begins early in life, and the studies conducted on cord blood lipid profile had inconsistent Preterm small for gestational age (sga) neonates had statistically. The high prevalence of cad and the undesirable lipid profile of the iranian children and adolescents led us to test plasma lipid profiles of umbilical cord blood in iranian newborns 6, 20, 38.
Lpa concentrations are genetically determined, thus conferring an important role in the assessment of genetically increased cardiovascular risk 41 .
Cord blood lipid profile and insulin levels: The observation in cord blood reveals to study the risk factor variable in the early stage. Multiple linear regression models were developed to estimate the association of exposure to air pollution and traffic indicators with cord blood lipid profile controlled for relevant covariates. Detection of lipid profile in umbilical cord blood of term newborns could identify neonates with a higher risk of coronary artery disease. Lpa concentrations are genetically determined, thus conferring an important role in the assessment of genetically increased cardiovascular risk 41 . There are a few studies which have compared the cord blood lipid profile of preterm and term babies and thereby leading a path to primordial prevention of chronic diseases. The high prevalence of cad and the undesirable lipid profile of the iranian children and adolescents led us to test plasma lipid profiles of umbilical cord blood in iranian newborns 6, 20, 38. The lipid profile results of total cholesterol, triglycerides, high density lipoprotein, and low density lipoprotein were 69.8, 34.9, 23.6, and 31.5 in term neonates and 80.5, 25.5, 25.1, and 38 in preterm neonates, respectively. The aim of the present study was for the first time in iran to assess the cord blood lipid profile of neonates, as well as some of its environmental influencing factors. The newborns' umbilical cord serum was analyzed for its lipid profile, including total cholesterol (tc), triglycerides (tg), high density lipoprotein (hdl), very low density lipoprotein (vldl. Cord blood lipid profile and insulin levels were compared between these two groups. After written and informed consent of parents cord blood was collected at birth and sent for lipid profile analysis. Cord blood sample from maternal side was also used to estimate lipid profile.
Mean cholesterol levels, triglyceride levels, ldl cholesterol levels and vldl levels were significantly higher in the sga group than that in the aga group (p < 0.01). Preterm small for gestational age (sga) neonates had statistically. The lipid profile results of total cholesterol, triglycerides, high density lipoprotein, and low density lipoprotein were 69.8, 34.9, 23.6, and 31.5 in term neonates and 80.5, 25.5, 25.1, and 38 in preterm neonates, respectively. Which means that dcc decrease lipid transfer from mother to fetus. Cases having family history of cad and ht have hypertriglyceridemia, hypercholesterolemia and hyperlipidemia and have risk of developing atherosclerosis in their later life.
There are a few studies which have compared the cord blood lipid profile of preterm and term babies and thereby leading a path to primordial prevention of chronic diseases. However, other maternal and intrauterine factors might directly impact neonatal lipid parameters. The relationship between cord blood lipid profile with bmi and gestational age of the study population is presented in. Table 2presents the relationship of cord blood lipid profile with birth weight and gestational age. Atherosclerosis originates during childhood and the serum lipid levels are a key factor in the process. Atherosclerosis may originate during the fetal period, therefore it is reasonable to identify early risk markers of lifestyle diseases. Atherosclerosis begins early in life, and the studies conducted on cord blood lipid profile had inconsistent The atherogenic index of plasma (aip) also was calculated.
Cord blood samples were collected from placental side of umbilical cord at birth and analyzed for lipid profile which includes serum cholesterol, triglycerides, low density lipoprotein (ldl), high density lipoprotein (hdl) and apolipoproteins which include apoa1, apo b.
Preterm small for gestational age (sga) neonates had statistically. Statistical analyses was done using spss 21 software results: Cord blood samples were collected from placental side of umbilical cord at birth and analyzed for lipid profile which includes serum cholesterol, triglycerides, low density lipoprotein (ldl), high density lipoprotein (hdl) and apolipoproteins which include apoa1, apo b. The distribution of newborns according to their total cholesterol levels is depicted in figure 1. Cord blood lipid profiles in a population of iranian term newborns. During pregnancy, as well as in fetal development, there is high demand of choline 15 , thus it is conceivable that insufficient maternal choline availability may have mediated the downregulation in phospholipid levels in the. Atherosclerosis originates during childhood and the serum lipid levels are a key factor in the process. In the study group, there were 206 healthy polish newborns. The cord blood lipid parameters screening of neonates in this part of southern rajasthan were almost comparable with other reports. The roots of this epidemic have been traced to as early as foetal life by foetal origin hypothesis. Atherosclerosis begins early in life, and the studies conducted on cord blood lipid profile had inconsistent The aim of the present study was for the first time in iran to assess the cord blood lipid profile of neonates, as well as some of its environmental influencing factors. Lipid metabolism neonate bis investigator group science & technology life sciences & biomedicine pediatrics fatty children disease cohort health:
There is evidence that cord blood lipid levels may partly reflect the maternal lipid profile during late pregnancy. During pregnancy, as well as in fetal development, there is high demand of choline 15 , thus it is conceivable that insufficient maternal choline availability may have mediated the downregulation in phospholipid levels in the. Cord blood lipids were lower in the dcc group than the ecc group. The aim of the study was to determine the relationship between fetal and maternal factors, and the neonatal cord blood lipid profile in term newborns. Cases having family history of cad and ht have hypertriglyceridemia, hypercholesterolemia and hyperlipidemia and have risk of developing atherosclerosis in their later life.
Cord blood lipid profiles in a population of iranian term newborns. Atherosclerosis begins early in life, and the studies conducted on cord blood lipid profile had inconsistent The roots of this epidemic have been traced to as early as foetal life by foetal origin hypothesis. Cord blood lipids were lower in the dcc group than the ecc group. The mean gestational age in term and preterm neonates was 39.16 ± 1.01 weeks and 33.13 ± 3.28 weeks and birth weight was 3.13 ± 0.45 kg and 2.04 ± 0.55 kg respectively. Among various factors theorized in the development of atherosclerosis, increased plasma levels of cholesterol and or triglycerides are considered to be of most important factors. Field of research 1103 clinical sciences 1114 paediatrics and reproductive medicine Atherosclerosis may originate during the fetal period, therefore it is reasonable to identify early risk markers of lifestyle diseases.
Lipid metabolism neonate bis investigator group science & technology life sciences & biomedicine pediatrics fatty children disease cohort health:
Cord blood samples were collected from placental side of umbilical cord at birth and analyzed for lipid profile which includes serum cholesterol, triglycerides, low density lipoprotein (ldl), high density lipoprotein (hdl) and apolipoproteins which include apoa1, apo b. Detection of lipid profile in umbilical cord blood of term newborns could identify neonates with a higher risk of coronary artery disease. Cord blood lipids were lower in the dcc group than the ecc group. Lipid profile was compared between preterm and term neonates, sga and aga neonates. Among various factors theorized in the development of atherosclerosis, increased plasma levels of cholesterol and or triglycerides are considered to be of most important factors. The lipid profile results of total cholesterol, triglycerides, high density lipoprotein, and low density lipoprotein were 69.8, 34.9, 23.6, and 31.5 in term neonates and 80.5, 25.5, 25.1, and 38 in preterm neonates, respectively. Coronary heart disease is one of the major causes of morbidity and mortality in current era. Lpa concentrations are genetically determined, thus conferring an important role in the assessment of genetically increased cardiovascular risk 41 . Atherosclerosis begins early in life, and the studies conducted on cord blood lipid profile had inconsistent However, other maternal and intrauterine factors might directly impact neonatal lipid parameters. Statistical analyses was done using spss 21 software results: The aim of the present study was to improve the existing information about cord blood lipid profile of iranian term newborns. Table 2presents the relationship of cord blood lipid profile with birth weight and gestational age.